Case 1:

  • Pathogenesis of HBV associated PAN is thought to be a combination of deposition of immune complexes in antigen excess
  • Goal is to clear immune complexes and suppress viral replication to achieve seroconversion (HBe antigen to HBe antibody), but treatments are limited
  • GI related complications highest cause of mortality
  • HBV related PAN cases have gone down as a result of safer blood transfusions and mass vaccination campaigns

Case 2

  • Strongyloides is a widely prevalent helminthic infection that rarely can lead to a hyperinfection syndrome
  • Consider Strongyloides as a cause of upper GI bleeding if diffuse ulceration and friability is present
  • Steroids can cause Strongyloides hyperinfection syndrome, which is extremely morbid
  • Ensure that patients starting any form of immunosuppression at high-risk of exposure get screened for Strongyloides prior to starting treatment

Alexander Goldowsky, MD, Presenter, has no relevant financial relationships to disclose

Session date: 
08/04/2022 - 12:15pm to 1:00pm EDT
Location: 
Boston University School of Medicine
United States
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  • 0.75 AMA PRA Category 1 Credit™

    Boston University Chobanian & Avedisian School of Medicine designates this Live activity for a maximum of 0.75 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

  • 0.75 Participation
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